A Functional 3D Biomimetic Osteon Accelerates Bone Regeneration

Chenxu Zhu, Zexi Li, Xubin Qiu, Baizhen Zhao, Huan Wang, Lijie Wang, Ming Zhuang, Jinbo Liu, Fengxuan Han, Bin Li

期刊: ADVANCED FUNCTIONAL MATERIALS |  发表时间: 2025-03-26 |  DOI: 10.1002/adfm.202500603 |  影响因子: 19.0

研究领域: 组织工程, 再生医学, 生物材料科学, 生物医学工程

Differentiation Responsive Architected Macrophage (DREAM) Selectively Modulate Tumor Microenvironment for Cancer Immunotherapy

Haoting Chen, Ding Yang, Dongyue He, Zechuan Li, Gengyou Li, Jing Ma, Jiaqing Wan, Meifen Luo, Qi Chen, Yansong Liu, Qihan Zhang, Yanwen Liang, Ying-Shi Sun, Weisheng Guo, Lu Liu

期刊: ADVANCED FUNCTIONAL MATERIALS |  发表时间: 2025-05-20 |  DOI: 10.1002/adfm.202503583 |  影响因子: 19.0

研究领域: 肿瘤学, 免疫学, 纳米医学

A proximity-induced chimera platform for targeted protein arginine methylation

Yanlin Jian, Tianyang Zhou, Chendong Guo, Yibo Gao, Chen Yao, Zixi Wang, Xuehan Jiang, Ke Wang, Jian Ma, Yang Gao, Yizeng Fan, Jing Liu, Bohan Ma, Lei Li

期刊: Acta Pharmaceutica Sinica B |  发表时间: 2025-04-04 |  DOI: 10.1016/j.apsb.2025.03.049 |  影响因子: 14.6

研究领域: 生物化学, 分子生物学, 细胞信号传导, 治疗学

Fusobacterium nucleatum‐Derived Outer Membrane Vesicles Promote Immunotherapy Resistance via Changes in Tryptophan Metabolism in Tumour‐Associated Macrophages

Weiping Li, Zhen Zhang, Ruoyi Wu, Mengying Mao, Yikang Ji, Xiaoning Wang, Shengjin Dou, Ming Yan, Wantao Chen

期刊: Journal of Extracellular Vesicles |  发表时间: 2025-04-16 |  DOI: 10.1002/jev2.70070 |  影响因子: 14.5

研究领域: 微生物学, 免疫学, 肿瘤学

Locoregional Immune Checkpoint Blockade and Remodeling of Lymph Nodes by Engineered Dendritic Cell-Derived Exosomes for Suppressing Tumor Progression and Metastasis

Yizhen Wang, Xiaomin Guo, Jingya Qin, Yifan Xue, Peng Zhang, Yadong Liu, Moyang Chen, Guanghao Zhu, Xinqiu Song, Lili Cheng, Bo Liu, Jie Liu, Jie Ren

期刊: Advanced Science |  发表时间: 2025-04-03 |  DOI: 10.1002/advs.202500139 |  影响因子: 14.1

研究领域: 肿瘤学, 免疫学

PP2A Promotes the Symmetric Division of MUC1-Dominant Cancer Stem-Like Cells in Small Cell Lung Cancer

Shengze Li, Xinran Dong, Kexing Gao, Yiyang Wang, Min Li, Huayun Deng, Shuangyu Ma, Yaping Lv, Wei Jin, Quanfu Li, Yuming Wang, Xiaodong Liao, Kangjing Bian, Aiwu Zhou, Chengping Hu, Lei Huang

期刊: Advanced Science |  发表时间: 2025-05-11 |  DOI: 10.1002/advs.202503545 |  影响因子: 14.1

研究领域: 肿瘤学, 分子生物学, 医学

Activation of HTR2B Suppresses Osteosarcoma Progression through the STAT1-NLRP3 Inflammasome Pathway and Promotes OASL1+ Macrophage Production to Enhance Antitumor Immunity

Zhen Huang, Jiazhuang Zhu, Jianping Hu, Xingkai Wang, Xiaolong Ma, Enjie Xu, Kunpeng Zhu, Chunlin Zhang

期刊: Advanced Science |  发表时间: 2025-05-19 |  DOI: 10.1002/advs.202415276 |  影响因子: 14.1

研究领域: 肿瘤学, 免疫学, 分子生物学

CTCF enhances pancreatic cancer progression via FLG-AS1-dependent epigenetic regulation and macrophage polarization

Liu Yihao, Liu Pengyi, Duan Songqi, Lin Jiayu, Qi Wenxin, Yu Zhengwei, Gao Xia, Sun Xiuqiao, Liu Jia, Lin Jiewei, Zhai Shuyu, Qin Kai, Cao Yizhi, Li Jingwei, Liu Yang, Chen Mengmin, Zou Siyi, Wen Chenlei, Wang Jiao, Fu Da, Wang Jiancheng, Bao Haili, Sun Keyan, Jiang Yu, Shen Baiyong

期刊: CELL DEATH AND DIFFERENTIATION |  发表时间: 2024-11-30 |  DOI: 10.1038/s41418-024-01423-1 |  影响因子: 13.7

研究领域: 肿瘤学, 表观遗传学, 免疫治疗, 分子生物学, 癌症生物学

Zirconium phosphate nanonetworks for enhanced soft tissue integration and antibacterial performance of zirconia implant abutments

Yingyue Sun, Qihong Zhang, Shuyi Wu, Kendrick Hii Ru Yie, Lei Cai, Yinyan Zhang, Wen Si, Huan Cheng, Zijian Zheng, Peng Gao, Lei Lu, Jinsong Liu

期刊: CHEMICAL ENGINEERING JOURNAL |  发表时间: 2025-04-25 |  DOI: 10.1016/j.cej.2025.163090 |  影响因子: 13.2

研究领域: 牙科材料, 生物材料科学, 组织工程, 微生物学

Inflammation-driven biomimetic nano-polyphenol drug delivery system alleviates severe acute pancreatitis by inhibiting macrophage PANoptosis and pancreatic enzymes oversecretion

Junyong Wu, Hai Huang, Wenjie Xu, Beibei Cui, Pengcheng Sun, XinYan Hao, Shihe Jiang, Xuyang Hou, Xiaoyan Qi, Zuxing Wei, Yimiao Cheng, Yanwen Zheng, Kuijie Liu, Jun He

期刊: Journal of Advanced Research |  发表时间: 2025-04-08 |  DOI: 10.1016/j.jare.2025.04.006 |  影响因子: 13.0

研究领域: 药理学, 生物医学工程, 炎症研究