Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice

Wang Meng, Feng Li-Rong, Li Zi-Long, Ma Kai-Ge, Chang Ke-Wei, Chen Xin-Lin, Yang Peng-Bo, Ji Sheng-Feng, Ma Yan-Bing, Han Hua, Ruganzua John Bosco, Yang Wei-Na, Qian Yi-Hua

期刊: Journal of Neuroinflammation |  发表时间: 2021-06-28 |  DOI: 10.1186/s12974-021-02166-3 |  影响因子: 8.322

研究领域: 神经科学, 药理学, 分子生物学, 神经退行性疾病

In-cell bioluminescence resonance energy transfer (BRET)-based assay uncovers ceritinib and CA-074 as SARS-CoV-2 papain-like protease inhibitors

Mei Li, Zhu-Chun Bei, Yongtian Yuan, Baogang Wang, Dongna Zhang, Likun Xu, Liangliang Zhao, Qin Xu, Yabin Song

期刊: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |  发表时间: 2024-08-20 |  DOI: 10.1080/14756366.2024.2387417 |  影响因子: 5.6

研究领域: 病毒学, 药理学, 分子生物学

Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug

Yu-Chuan Wang, Wen-Hao Yang, Chia-Shin Yang, Mei-Hui Hou, Chia-Ling Tsai, Yi-Zhen Chou, Mien-Chie Hung, Yeh Chen

期刊: American Journal of Cancer Research |  发表时间: 2020-08-01 |  DOI: PMID:32905393 |  影响因子: 5.177

研究领域: 病毒学, 结构生物学, 药物开发, 传染病学

Characterization of Recombinant Flaviviridae Viruses Possessing a Small Reporter Tag

Tomokazu Tamura, Takasuke Fukuhara, Takuro Uchida, Chikako Ono, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Takeshi Kurosu, Yin Xiang Setoh, Michio Imamura, Norbert Tautz, Yoshihiro Sakoda, Alexander A. Khromykh, Kazuaki Chayama, Yoshiharu Matsuura

期刊: JOURNAL OF VIROLOGY |  发表时间: 2018-01-02 |  DOI: 10.1128/jvi.01582-17 |  影响因子: 4.368

研究领域: 病毒学, 分子生物学, 传染病学