ESRP1-mediated biogenesis of circPTPN12 inhibits hepatocellular carcinoma progression by PDLIM2/ NF-κB pathway

Ji Yang, Ni Chuangye, Shen Yanjun, Xu Zhenggang, Tang Lei, Yu Fei, Zhu Lingbang, Lu Hao, Zhang Chuanyong, Yang Shikun, Wang Xuehao

期刊: Molecular Cancer |  发表日期: 2024-07-11 |  DOI: 10.1186/s12943-024-02056-1 |  影响因子: 27.7

研究领域:  肿瘤学, 分子生物学, 癌症生物学

Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance

Cui Jianfeng, Liu Xiaochen, Shang Qinghong, Sun Shuna, Chen Shouzhen, Dong Jianping, Zhu Yaofeng, Liu Lei, Xia Yangyang, Wang Yong, Xiang Lu, Fan Bowen, Zhan Jiafeng, Zhou Yadi, Chen Pengxiang, Zhao Renchang, Liu Xiaofei, Xing Nianzeng, Wu Dalei, Shi Benkang, Zou Yongxin

期刊: Molecular Cancer |  发表日期: 2024-04-29 |  DOI: 10.1186/s12943-024-01996-y |  影响因子: 27.7

研究领域:  癌症生物学, 分子生物学, 细胞生物学, 药理学

PDPN positive CAFs contribute to HER2 positive breast cancer resistance to trastuzumab by inhibiting antibody-dependent NK cell-mediated cytotoxicity

Ruoxin Du, Xiangmei Zhang, Xiyan Lu, Xiangmin Ma, Xinyan Guo, Chao Shi, Xiaofei Ren, Xindi Ma, Yutong He, Yuan Gao, Yunjiang Liu

期刊: DRUG RESISTANCE UPDATES |  发表日期: 2023-02-09 |  DOI: 10.1016/j.drup.2023.100947 |  影响因子: 24.3

研究领域:  肿瘤学, 免疫学, 癌症生物学

A Mucous Permeable Local Delivery Strategy Based on Manganese-Enhanced Bacterial Cuproptosis-like Death for Bacterial Pneumonia Treatment

Shiyuan Hua, Huiqun Hu, Jin Liu, Feng Lu, Runchang Yu, Xuening Zhang, Haimeng Sun, Ziwei Wang, Yige Li, Jingyan Xia, Feng Xu, Min Zhou

期刊: ACS Nano |  发表日期: 2024-11-07 |  DOI: 10.1021/acsnano.4c09695 |  影响因子: 15.8

研究领域:  药学, 纳米技术, 传染病学, 材料科学, 生物医学工程

Self-Sulfhydrated, Nitro-Fixed Albumin Nanoparticles as a Potent Therapeutic Agent for the Treatment of Acute Liver Injury

Yanan Wang, Xiaohu Liu, Keyang Li, Xinyuan Wang, Xue Zhang, Deyao Qian, Xinlei Meng, Liangmin Yu, Xuefeng Yan, Zhiyu He

期刊: ACS Nano |  发表日期: 2024-07-23 |  DOI: 10.1021/acsnano.4c07297 |  影响因子: 15.8

研究领域:  药理学, 纳米技术, 肝病学, 分子生物学, 治疗学

BCAT2 Shapes a Noninflamed Tumor Microenvironment and Induces Resistance to Anti-PD-1/PD-L1 Immunotherapy by Negatively Regulating Proinflammatory Chemokines and Anticancer Immunity

Zhiyong Cai, Jinbo Chen, Zhengzheng Yu, Huihuang Li, Zhi Liu, Dingshan Deng, Jinhui Liu, Chunliang Chen, Chunyu Zhang, Zhenyu Ou, Minfeng Chen, Jiao Hu, Xiongbing Zu

期刊: Advanced Science |  发表日期: 2023-01-15 |  DOI: 10.1002/advs.202207155 |  影响因子: 15.1

研究领域:  肿瘤学, 免疫学, 分子生物学, 癌症治疗

Increased PRP19 in Hepatocyte Impedes B Cell Function to Promote Hepatocarcinogenesis

Zhiyong Liu, Xiahui Lin, Danying Zhang, Dezhen Guo, Wenqing Tang, Xiangnan Yu, Feng Zhang, Si Zhang, Ruyi Xue, Xizhong Shen, Ling Dong

期刊: Advanced Science |  发表日期: 2024-10-18 |  DOI: 10.1002/advs.202407517 |  影响因子: 14.3

研究领域:  肿瘤学, 免疫学, 分子生物学, 癌症生物学

Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington's disease

Chunyue Liu, Zixing Fu, Shanshan Wu, Xiaosong Wang, Shengrong Zhang, Chu Chu, Yuan Hong, Wenbo Wu, Shengqi Chen, Yueqing Jiang, Yang Wu, Yongbo Song, Yan Liu, Xing Guo

期刊: EMBO Molecular Medicine |  发表日期: 2022-06-07 |  DOI: 10.15252/emmm.202215851 |  影响因子: 14.26

研究领域:  神经科学, 分子生物学, 遗传学, 细胞生物学

CTCF enhances pancreatic cancer progression via FLG-AS1-dependent epigenetic regulation and macrophage polarization

Liu Yihao, Liu Pengyi, Duan Songqi, Lin Jiayu, Qi Wenxin, Yu Zhengwei, Gao Xia, Sun Xiuqiao, Liu Jia, Lin Jiewei, Zhai Shuyu, Qin Kai, Cao Yizhi, Li Jingwei, Liu Yang, Chen Mengmin, Zou Siyi, Wen Chenlei, Wang Jiao, Fu Da, Wang Jiancheng, Bao Haili, Sun Keyan, Jiang Yu, Shen Baiyong

期刊: CELL DEATH AND DIFFERENTIATION |  发表日期: 2024-11-30 |  DOI: 10.1038/s41418-024-01423-1 |  影响因子: 13.7

研究领域:  肿瘤学, 表观遗传学, 免疫治疗, 分子生物学, 癌症生物学

Biomimetic nanovesicles-based therapeutic strategy for alleviating intervertebral disc degeneration via integration with mechanically responsive miR-1249

Jiangbo Guo, Yilin Yang, Li Ni, Haifei Cao, Hao Shen, Zongping Luo, Junjie Niu, Huilin Yang, Qin Shi

期刊: Nano Today |  发表日期: 2024-03-11 |  DOI: 10.1016/j.nantod.2024.102221 |  影响因子: 13.2

研究领域:  生物医学工程, 分子生物学, 骨科, 纳米技术, 再生医学