Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance

Cui Jianfeng, Liu Xiaochen, Shang Qinghong, Sun Shuna, Chen Shouzhen, Dong Jianping, Zhu Yaofeng, Liu Lei, Xia Yangyang, Wang Yong, Xiang Lu, Fan Bowen, Zhan Jiafeng, Zhou Yadi, Chen Pengxiang, Zhao Renchang, Liu Xiaofei, Xing Nianzeng, Wu Dalei, Shi Benkang, Zou Yongxin

期刊: Molecular Cancer |  发表时间: 2024-04-29 |  DOI: 10.1186/s12943-024-01996-y |  影响因子: 27.7

研究领域: 癌症生物学, 分子生物学, 细胞生物学, 药理学

ESRP1-mediated biogenesis of circPTPN12 inhibits hepatocellular carcinoma progression by PDLIM2/ NF-κB pathway

Ji Yang, Ni Chuangye, Shen Yanjun, Xu Zhenggang, Tang Lei, Yu Fei, Zhu Lingbang, Lu Hao, Zhang Chuanyong, Yang Shikun, Wang Xuehao

期刊: Molecular Cancer |  发表时间: 2024-07-11 |  DOI: 10.1186/s12943-024-02056-1 |  影响因子: 27.7

研究领域: 肿瘤学, 分子生物学, 癌症生物学

PDPN positive CAFs contribute to HER2 positive breast cancer resistance to trastuzumab by inhibiting antibody-dependent NK cell-mediated cytotoxicity

Ruoxin Du, Xiangmei Zhang, Xiyan Lu, Xiangmin Ma, Xinyan Guo, Chao Shi, Xiaofei Ren, Xindi Ma, Yutong He, Yuan Gao, Yunjiang Liu

期刊: DRUG RESISTANCE UPDATES |  发表时间: 2023-02-09 |  DOI: 10.1016/j.drup.2023.100947 |  影响因子: 24.3

研究领域: 肿瘤学, 免疫学, 癌症生物学

Self-Sulfhydrated, Nitro-Fixed Albumin Nanoparticles as a Potent Therapeutic Agent for the Treatment of Acute Liver Injury

Yanan Wang, Xiaohu Liu, Keyang Li, Xinyuan Wang, Xue Zhang, Deyao Qian, Xinlei Meng, Liangmin Yu, Xuefeng Yan, Zhiyu He

期刊: ACS Nano |  发表时间: 2024-07-23 |  DOI: 10.1021/acsnano.4c07297 |  影响因子: 15.8

研究领域: 药理学, 纳米技术, 肝病学, 分子生物学, 治疗学

A Mucous Permeable Local Delivery Strategy Based on Manganese-Enhanced Bacterial Cuproptosis-like Death for Bacterial Pneumonia Treatment

Shiyuan Hua, Huiqun Hu, Jin Liu, Feng Lu, Runchang Yu, Xuening Zhang, Haimeng Sun, Ziwei Wang, Yige Li, Jingyan Xia, Feng Xu, Min Zhou

期刊: ACS Nano |  发表时间: 2024-11-07 |  DOI: 10.1021/acsnano.4c09695 |  影响因子: 15.8

研究领域: 药学, 纳米技术, 传染病学, 材料科学, 生物医学工程

BCAT2 Shapes a Noninflamed Tumor Microenvironment and Induces Resistance to Anti-PD-1/PD-L1 Immunotherapy by Negatively Regulating Proinflammatory Chemokines and Anticancer Immunity

Zhiyong Cai, Jinbo Chen, Zhengzheng Yu, Huihuang Li, Zhi Liu, Dingshan Deng, Jinhui Liu, Chunliang Chen, Chunyu Zhang, Zhenyu Ou, Minfeng Chen, Jiao Hu, Xiongbing Zu

期刊: Advanced Science |  发表时间: 2023-01-15 |  DOI: 10.1002/advs.202207155 |  影响因子: 15.1

研究领域: 肿瘤学, 免疫学, 分子生物学, 癌症治疗

Increased PRP19 in Hepatocyte Impedes B Cell Function to Promote Hepatocarcinogenesis

Zhiyong Liu, Xiahui Lin, Danying Zhang, Dezhen Guo, Wenqing Tang, Xiangnan Yu, Feng Zhang, Si Zhang, Ruyi Xue, Xizhong Shen, Ling Dong

期刊: Advanced Science |  发表时间: 2024-10-18 |  DOI: 10.1002/advs.202407517 |  影响因子: 14.3

研究领域: 肿瘤学, 免疫学, 分子生物学, 癌症生物学

Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington's disease

Chunyue Liu, Zixing Fu, Shanshan Wu, Xiaosong Wang, Shengrong Zhang, Chu Chu, Yuan Hong, Wenbo Wu, Shengqi Chen, Yueqing Jiang, Yang Wu, Yongbo Song, Yan Liu, Xing Guo

期刊: EMBO Molecular Medicine |  发表时间: 2022-06-07 |  DOI: 10.15252/emmm.202215851 |  影响因子: 14.26

研究领域: 神经科学, 分子生物学, 遗传学, 细胞生物学

Improved Efficacy of Triple-Negative Breast Cancer Immunotherapy via Hydrogel-Based Co-Delivery of CAR-T Cells and Mitophagy Agonist

Guodong Li, Ruoxin Du, Donghui Wang, Xiangmei Zhang, Lizhuo Wang, Shuangpeng Pu, Xiaoju Li, Shuning Wang, Juliang Zhang, Beichen Liu, Yuan Gao, Huadong Zhao

期刊: Advanced Science |  发表时间: 2025-01-22 |  DOI: 10.1002/advs.202409835 |  影响因子: 14.1

研究领域: 肿瘤学, 免疫学, 生物医学工程, 癌症治疗

Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation

Manyu Xing, Shuang Liang, Wei Cao, Qulian Guo, Wangyuan Zou

期刊: Advanced Science |  发表时间: 2025-03-28 |  DOI: 10.1002/advs.202416904 |  影响因子: 14.1

研究领域: 免疫学, 分子生物学, 细胞生物学, 重症医学